Invitrogen™ TAF11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565545

Catalog No. PIPA565545

Description

Immunogen sequence: KEAAAEEGELE SQDVSDLTTV EREDSSLLNP AAKKLKIDTK EKKEKKQKVD EDEIQKMQIL VSSFSEEQLN RYEMYRR Highest antigen sequence identity to the following orthologs - mouse 87%, rat 88%.

TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.

Specifications

• Antigen: TAF11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAF11
• Gene Alias: 1110038O14Rik; 28kDa; AI115401; AL024207; AW552398; hypothetical protein LOC507047; MGC:15243; PRO2134; PRO214; TAF(II)28; Taf11; TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa; TAF2I; TAFII28; TAFII-28; TATA box binding protein (TBP)-associated factor 11; TATA box binding protein (TBP)-associated factor, RNA polymerase II, I, 28kD; TATA box binding protein associated factor 11; TATA-box binding protein associated factor 11; TBP-associated factor 11; TFIID subunit p30-beta; transcription initiation factor TFIID 28 kD subunit; transcription initiation factor TFIID 28 kDa subunit; Transcription initiation factor TFIID subunit 11
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6882
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.6 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15544
• Gene Symbols: TAF11
• Immunogen: Recombinant Human TAF11. Recombinant protein control fragment (Product #RP-104868).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov