Invitrogen™ TAF11 Polyclonal Antibody

Catalog No.	Quantity
PIPA596868	100 μL

Catalog No. PIPA596868 Supplier Invitrogen™ Supplier No. PA596868

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDDAHESPSD KGGETGESDE TAAVPGDPGA TDTDGIPEET DGDADVDLKE AAAEEGELES QDVSDLTTVE REDSSLLNPA AKKLKIDTKE KKEKKQKVDE DEIQKMQILV SSFSEEQLNR YEMYRRSAFP KAAIKRLIQS ITGTSVSQNV VIAMSGISKV FVGEVVEEAL DVCEKWGEMP PLQPKHMREA VRRLKSKGQI PNSKHKKIIF F; Positive Samples: HeLa, SW620; Cellular Location: Nucleus.

TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.

Specifications

• Antigen: TAF11
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.84 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: TAF11
• Gene Accession No.: Q15544, Q99JX1
• Gene Alias: 1110038O14Rik; 28kDa; AI115401; AL024207; AW552398; hypothetical protein LOC507047; MGC:15243; PRO2134; PRO214; TAF(II)28; Taf11; TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa; TAF2I; TAFII28; TAFII-28; TATA box binding protein (TBP)-associated factor 11; TATA box binding protein (TBP)-associated factor, RNA polymerase II, I, 28kD; TATA box binding protein associated factor 11; TATA-box binding protein associated factor 11; TBP-associated factor 11; TFIID subunit p30-beta; transcription initiation factor TFIID 28 kD subunit; transcription initiation factor TFIID 28 kDa subunit; Transcription initiation factor TFIID subunit 11
• Gene Symbols: TAF11
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human TAF11 (NP_0056341).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 68776, 6882
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG