Invitrogen™ TAF12 Monoclonal Antibody (22TA-2A1)

Catalog No.	Quantity
PIMA3072	50 μL

Catalog No. PIMA3072 Supplier Invitrogen™ Supplier No. MA3072

Description

Mouse Monoclonal Antibody

MA3-072 detects TATA-Binding Protein (TBP) Associated factor 12 in the human samples. MA3-072 has been successfully used in Western blot, immunofluorescence, and flow cytometry applications. The MA3-072 immunogen is a recombinant human TAF12 protein. Epitope is localized at the C-terminal part of TAF12.

TAF12 is involved in the control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I.

Specifications

• Antigen: TAF12
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 22TA-2A1
• Concentration: Conc. Not Determined
• Conjugate: Unconjugated
• Formulation: ascites with 0.05% sodium azide
• Gene: TAF12
• Gene Accession No.: Q16514
• Gene Alias: 20kDa; 2810422D08Rik; AW557038; hypothetical protein LOC614227; TAF12; TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20 kD; TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20 kDa; TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa; TAF15; TAF2J; TAFII20; TAFII-20; TAFII20/TAFII15; TAFII-20/TAFII-15; TATA box binding protein (TBP)-associated factor, RNA polymerase II, J, 20kD; TATA box binding protein associated factor 12; TATA-box binding protein associated factor 12; TATA-box binding protein associated factor 12; transcription initiation factor TFIID subunit 12; transcription initiation factor TFIID 20 kDa subunits; Transcription initiation factor TFIID 20/15 kDa subunits; transcription initiation factor TFIID subunit 12
• Gene Symbols: TAF12
• Host Species: Mouse
• Immunogen: Recombinant human TAF12 protein. Epitope localized at the C-terminal part of TAF12.
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6883
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ