Invitrogen™ TAF1C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593203

Catalog No. PIPA593203

Description

Immunogen sequence: PPLIDPWDPG LTARDLLFRG GYRYRKRPRV VLDVTEQISR FLLDHGDVAF APLGKLMLEN FKLEGAGSRT KKKTVVSVKK LLQDLGGHQP WGCPWAYLSN RQRRFSILGG PILGTSVASH LAELLHEELV LRWEQLLLDE ACTGGALAWV PGRTPQFGQL VYPAGGAQDR LHFQEVVLTP GDNPQFLGKP GRIQLQGPVR QVVTCTVQGE TLLAVRSDYH CAVWKFGKQW QPTLLQAMQV EKGATGISLS P; Positive Samples: 293T, MCF7, Mouse thymus; Cellular Location: Nucleus.

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.

Specifications

• Antigen: TAF1C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAF1C
• Gene Alias: MGC:39976; mTAFI95; RNA polymerase I-specific TBP-associated factor 110 kDa; RNA polymerase I-specific TBP-associated factor 95 kDa; SL1; SL1, 110kD subunit; TAF1C; TAFI110; TAFI95; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C; transcription factor TAFI95; TATA box binding protein associated factor 1C; TATA box-binding protein-associated factor 1C; TATA box-binding protein-associated factor RNA polymerase I subunit C; TATA box-binding protein-associated factor, RNA polymerase I, subunit C; TATA-box binding protein associated factor, RNA polymerase I subunit C; TATA-box binding protein associated factor, RNA polymerase I, C; TBP-associated factor 1C; TBP-associated factor RNA polymerase I 95 kDa; transcription factor SL1; transcription factor TAFI95; transcription initiation factor SL1/TIF-IB subunit C
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21341, 361420, 9013
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q15572, Q6P773, Q6PDZ2
• Gene Symbols: TAF1C
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-320 of human TAF1C (NP_0012300851).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG