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Invitrogen™ TAF1C Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA544852
Description
Peptide sequence: MDFPSSLRPA LFLTGPLGLS DVPDLSFMCS WRDALTLPEA QPQNSENGAL Sequence homology: Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 77%; Rat: 93%.
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
Specifications
TAF1C | |
Polyclonal | |
Unconjugated | |
TAF1C | |
MGC:39976; mTAFI95; RNA polymerase I-specific TBP-associated factor 110 kDa; RNA polymerase I-specific TBP-associated factor 95 kDa; SL1; SL1, 110kD subunit; TAF1C; TAFI110; TAFI95; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C; transcription factor TAFI95; TATA box binding protein associated factor 1C; TATA box-binding protein-associated factor 1C; TATA box-binding protein-associated factor RNA polymerase I subunit C; TATA box-binding protein-associated factor, RNA polymerase I, subunit C; TATA-box binding protein associated factor, RNA polymerase I subunit C; TATA-box binding protein associated factor, RNA polymerase I, C; TBP-associated factor 1C; TBP-associated factor RNA polymerase I 95 kDa; transcription factor SL1; transcription factor TAFI95; transcription initiation factor SL1/TIF-IB subunit C | |
Rabbit | |
Affinity Chromatography | |
RUO | |
9013 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
Q15572 | |
TAF1C | |
Synthetic peptide directed towards the N-terminal of human TAF1C (aa 1-50). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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