Invitrogen™ TAF2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540710

Catalog No. PIPA540710

Description

Peptide sequence: RKRNVLELEI KQDYTSPGTQ KYVGPLKVTV QELDGSFNHT LQIEENSLKH Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%.

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators.

Specifications

• Antigen: TAF2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAF2
• Gene Alias: 150 kDa cofactor of initiator function; 150kDa; 4732460C16Rik; AI425886; CIF150; cofactor of initiator function, 150kD subunit; fc30f02; fc56a05; MRT40; RNA polymerase II TBP-associated factor subunit B; TAF(II)150; TAF150; TAF2; taf2 protein; TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa; TAF2 RNA polymerase II, TATA box binding protein-associated factor, 150 kD; TAF2B; Taf2p; TAFII150; TAFII-150; TAFIIB; TATA box binding protein (TBP)-associated factor 150kDa; TATA box binding protein (TBP)-associated factor, RNA polymerase II, B, 150kD; TATA box binding protein associated factor 2; TATA-box binding protein associated factor 2; TBP-associated factor 150 kDa; TBP-associated factor 2; transcription initiation factor TFIID 150 kDa subunit; Transcription initiation factor TFIID subunit 2; transcription initiation factor TFIID subunit 2-like protein; TSM1; TSM-1; wu:fc30f02; wu:fc56a05; YCR042C; YCR42C; YCR724
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6873
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ChIP Assay, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q6P1X5
• Gene Symbols: TAF2
• Immunogen: Synthetic peptide directed towards the middle region of human TAF2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG