Invitrogen™ TAF4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143943

Catalog No. PIPA5143943

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human A431 whole cell, human K562 whole cell, human Caco-2 whole cell, human U20S whole cell, human HepG2 whole cell, human PC-3 whole cell, rat brain tissue, mouse brain tissue. IHC: human ovarian serous adenocarcinoma tissue, human ovarian cancer tissue, human breast cancer tissue, human gastric adenocarcinoma tissue, human renal clear cell carcinoma tissue, human tonsil tissue, mouse brain tissue, rat brain tissue, human gastric adenocarcinoma tissue, human breast cancer tissue. ICC/IF: CACO-2 cell. Flow: Hela cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFkB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.

Specifications

• Antigen: TAF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAF4
• Gene Alias: 135kDa; AI450312; FLJ41943; LOW QUALITY PROTEIN: transcription initiation factor TFIID subunit 4; RNA polymerase II TBP-associated factor subunit C; TAF(II)130; TAF(II)135; TAF2C; TAF2C1; TAF4; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa; Taf4a; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135 kD; TAFII 130; TAFII 135; TAFII130; TAFII-130; TAFII135; TAFII-135; TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD; TATA box binding protein associated factor 4; TATA-box binding protein associated factor 4; TBP-associated factor 4; Transcription initiation factor TFIID 130 kDa subunit; transcription initiation factor TFIID 135 kD subunit; transcription initiation factor TFIID 135 kDa subunit; Transcription initiation factor TFIID subunit 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 228980, 682097, 6874
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: O00268
• Gene Symbols: TAF4
• Immunogen: E.coli-derived human TAF4 recombinant protein (Position: D6-K1085).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG