Invitrogen™ TAF5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536319

Catalog No. PIPA536319

Description

This antibody detects endogenous protein at a molecular weight of 87 kDa. Purity is >95% by SDS-PAGE.

TFIID is a general transcription factor which initiates preinitiation complex assembly through direct interaction with the TATA promoter element. It is a multisubunit complex consisting of a small TATA-binding polypeptide andother TATA-binding protein (TBP)-associated factors (TAFs). Although native TFIID can mediate both activator-independent (basal) and activator-dependent transcription in reconstituted systems, TBP can mediate only basal transcription. TAF II p100 (TBP-associated factor II100), also known as TAF5 or TAFII100, is the third largest subunit of human TFIID. It contains six WD40 repeats at the C-terminus and has an N-terminus capable of forming a flexible dimer. TAF II p100 plays an important role in forming the scaffold that is crucial for the assembly of the TFIID complex. TAF II p100 may also be involved in the stabilization of TAF interactions.

Specifications

• Antigen: TAF5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAF5
• Gene Alias: 6330528C20Rik; AV117817; TAF(II)100; TAF2D; TAF5; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa; TAFII100; TAFII-100; TATA box binding protein (TBP)-associated factor 2D; TATA box binding protein (TBP)-associated factor, RNA polymerase II, D, 100kD; TATA box binding protein associated factor 5; TATA-box binding protein associated factor 5; Tbp-associated factor 5; transcription initiation factor TFIID 100 kD subunit; transcription initiation factor TFIID 100 kDa subunit; Transcription initiation factor TFIID subunit 5
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 294018, 6877
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15542
• Gene Symbols: TAF5
• Immunogen: Synthetic peptide corresponding to amino acids 380-432 of human TAF II p100.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG