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TAF5 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A303685A

Encompass_Preferred

Catalog No. 50-156-5778


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Mouse

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex.
Specifications

Specifications

TAF5
Polyclonal
Unconjugated
TAF5
Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID 100 kDa subunit, TAF(II)100, TAFII-100, TAFII100, TAF5, TAF2D
Rabbit
Antigen affinity chromatography
RUO
6877
4° C
Liquid
Immunohistochemistry, Immunoprecipitation, Western Blot
1 mg/ml
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Q15542
TAF5
Between 1 and 50
100 μL
Primary
Human
Antibody
IgG
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