Invitrogen™ Tafolecimab Recombinant Human Monoclonal Antibody

Catalog No.	Quantity
PIMA542291	100 μg

Catalog No. PIMA542291

Supplier: Invitrogen™ MA542291

Description

Human Recombinant Monoclonal Antibody

Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

GPRC5D/CD3 bispecific antibody is used to treat multiple myeloma. The bispecific antibody is generically named tafolecimab. It is constructed using the Duobody technology authorized by Genmab. The heavy chain of the anti-CD3 antibody is introduced into F405L and R409K to construct the double antibody. S228P, F234A, and L235A mutations were also introduced into the IgG4 constant region.

Specifications

• Antigen: Tafolecimab
• Applications: ELISA, SDS-Page
• Classification: Recombinant Monoclonal
• Concentration: 1.02 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene Alias: IBI-306
• Host Species: Human
• Immunogen: Human PCSK9.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2 κ
• Target Molecule: Chemical

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov