TAG-72 Antibody (CA72/733), DyLight 350, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234591UV

Catalog No. NBP234591UV

Description

TAG-72 Monoclonal specifically detects TAG-72 in Human, Rat, Bovine, Canine samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: TAG-72
• Classification: Monoclonal
• Conjugate: DyLight 350
• Gene Alias: CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72
• Immunogen: Recombinant human TAG-72 protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 182875
• Target Species: Human, Rat, Bovine, Canine
• Form: Purified

• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: CA72/733
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Host Species: Mouse
• Molecular Weight of Antigen: 220 kDa
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

For Research Use Only