Invitrogen™ TAGAP Polyclonal Antibody

Catalog No.	Quantity
PIPA524442	400 μL

Catalog No. PIPA524442 Supplier Invitrogen™ Supplier No. PA524442

Description

Rabbit Polyclonal Antibody

TAGAP Polyclonal Antibody for Western Blot, IHC (P), Flow

TAGAP (T-cell activation Rho GTPase-activating protein) is a 731 amino acid protein that contains one Rho-GAP domain and exists as 4 alternatively spliced isoforms. TAGAP may function as a GTPase-activating protein and may play important roles during T-cell activation. The gene that encodes TAGAP contains approximately 10,685 bases and maps to human chromosome 6q25.3. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, are also located on chromosome 6. In addition, Stickler syndrome, hydroxylase deficiency and maple syrup urine disease are associated with genes on chromosome 6, while a bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

Specifications

• Antigen: TAGAP
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.4 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene: TAGAP
• Gene Accession No.: Q8N103
• Gene Alias: 2610315E15Rik; ARHGAP47; FKSG15; IDDM21; T cell activation Rho GTPase activating protein; Tagap; TAGAP1; T-cell activation GTPase activating protein; T-cell activation GTPase-activating protein; T-cell activation GTPase-activating protein 1; T-cell activation Rho GTPase-activating protein; T-cell activation RhoGTPase activating protein
• Gene Symbols: TAGAP
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide between 103-129 amino acids from the central region of human TAGAP.
• Purification Method: Antigen affinity chromatography, Protein A
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 117289
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG