Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Tocris Bioscience™ Takinib
GREENER_CHOICE

Catalog No. 64305
Click to view available options
Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Potent and selective TAK1/MAP3K7 kinase inhibitor

Takinib is a potent and selective TAK1/MAP3K7 kinase inhibitor (IC50 = 8.2-9.5 nM). Selective for TAK1 over IRAK4, IRAK1, GCK, CLK2 and MINK1 (IC50 values = 120, 390, 430, 430 and 1900 nM, respectively). Demonstrates weak inhibition at Src and Yes1. Exhibits no inhibition of MAP2K or other MAP3K family members. Induces apoptosis following TNF-α stimulation in in vitro models of rheumatoid arthritis and metastatic breast cancer.

Specifications

Chemical Name or Material N1-(1-Propyl-1 H-benzimidazol-2-yl)-1,3-benzenedicarboxamide
CAS 1111556-37-6
Quantity 5 mg
Target Other Kinase Inhibitors
Molecular Formula C18H18N4O2
Purity 0.98
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.