Invitrogen™ Talin 1 Monoclonal Antibody (2G10D2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA549244

Catalog No. PIMA549244

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human Raji whole cell, human SW620 whole cell, human COLO320 whole cell, human 293T whole cell, rat lung tissue, mouse lung tissue, mouse liver tissue. Flow: JK cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.

Specifications

• Antigen: Talin 1
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: P26039, Q9Y490
• Gene Symbols: TLN1
• Immunogen: E.coli-derived human Talin 1/TLN1 recombinant protein (Position: Q1658-N1876).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: 2G10D2
• Conjugate: Unconjugated
• Gene: TLN1
• Gene Alias: ILWEQ; KIAA1027; talin 1; talin-1; TLN; TLN1
• Host Species: Mouse
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21894, 313494, 7094
• Content And Storage: -20°C
• Form: Lyophilized