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Invitrogen™ TAOK2 Monoclonal Antibody (2F4)
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Catalog No. PIMA520685
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100 μg
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Catalog No. Quantity
PIMA520685 100 μg
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Catalog No. PIMA520685 Supplier Invitrogen™ Supplier No. MA520685
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Description

Mouse Monoclonal Antibody

Peptide Sequence: ELQCRQYKRK MLLARHSLDQ DLLREDLNKK QTQKDLECAL LLRQHEATRE LELRQLQAVQ RTRAELTRLQ HQTELGNQLE YNKRREQELR QKHAAQVRQQ.

TAOK2 (TAO1) is a serine/threonine kinase that may be an important regulator of the stress-responsive p38 MAP kinase pathway. In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TAOK2
Applications ELISA, Western Blot, Proximity Ligation Assay, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 2F4
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene TAOK2
Gene Accession No. Q9UL54
Gene Alias 1110033K02Rik; B230344N16; hKFC-C; Kiaa0881; Kinase from chicken homolog C; MAP3K17; mKIAA0881; prostate derived STE20-like kinase PSK; prostate-derived STE20-like kinase 1; prostate-derived sterile 20-like kinase 1; PSK; PSK1; PSK-1; PSK1-BETA; serine/threonine protein kinase TAO2; serine/threonine-protein kinase TAO2; serine-threonine kinase; tao; TAO kinase 2; TAO kinase 2TAO kinase 2; TAO1; TAO2; TAOK2; Thousand and one amino acid protein 2; thousand and one amino acid protein kinase 2; UNQ2971/PRO7431
Gene Symbols TAOK2
Host Species Mouse
Immunogen TAOK2 (AAH51798, 831 a.a. ~ 930 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9344
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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