Invitrogen™ Taok2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116716

Catalog No. PIPA5116716

Description

Positive Samples: MCF7, 293T Immunogen sequence: AEWLLRQKEQ LQQCQAEEEA GLLRRQRQYF ELQCRQYKRK MLLARHSLDQ DLLREDLNKK QTQKDLECAL LLRQHEATRE LELRQLQAVQ RTRAELTRLQ HQTELGNQLE YNKRREQELR Q.

TAOK2 (TAO1) is a serine/threonine kinase that may be an important regulator of the stress-responsive p38 MAP kinase pathway. In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.

Specifications

• Antigen: Taok2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAOK2
• Gene Alias: 1110033K02Rik; B230344N16; hKFC-C; Kiaa0881; Kinase from chicken homolog C; MAP3K17; mKIAA0881; prostate derived STE20-like kinase PSK; prostate-derived STE20-like kinase 1; prostate-derived sterile 20-like kinase 1; PSK; PSK1; PSK-1; PSK1-BETA; serine/threonine protein kinase TAO2; serine/threonine-protein kinase TAO2; serine-threonine kinase; tao; TAO kinase 2; TAO kinase 2TAO kinase 2; TAO1; TAO2; TAOK2; Thousand and one amino acid protein 2; thousand and one amino acid protein kinase 2; UNQ2971/PRO7431
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9344
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.24 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9UL54
• Gene Symbols: TAOK2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 610-730 of human TAOK2 (NP_0572352).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG