TAOK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-3309	150 μL

Catalog No. 50-173-3309 Supplier Proteintech Group Inc Supplier No. 211881AP150UL

Description

Rabbit Polyclonal Antibody

The immunogen of this antibody is 742-969 aa of human TAOK2 protein isoform Alpha. This antibody mainly detects the isoforms 1, 3, and 4. It does not detect isoform 2.

In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.

Specifications

• Antigen: TAOK2
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.26 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: TAOK2
• Gene Accession No.: Q6ZQ29, Q9JLS3, Q9UL54
• Gene Alias: hKFC C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK, PSK 1, PSK1, TAO kinase 2, TAO1, TAO2, TAOK2
• Gene Symbols: Taok2
• Host Species: Rabbit
• Immunogen: TAOK2 Fusion Protein Ag15521
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 381921, 64666, 9344
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG