Invitrogen™ TAP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521412

Catalog No. PIPA521412

Description

Recommended positive controls: 293T, A431, HeLaS3, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (98%), Rat (97%), Pig (96%), Chimpanzee (100%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The constitutive transport element (CTE) of type D retroviruses serves as a signal of nuclear export for unspliced viral RNAs. TAP (also known as NXF1) mediates the export of CTE-containing simian type D retroviral RNAs through binding directly to the CTE. TAP is associated with a recognized mRNA export pathway and is a member of the multigene family of NXF proteins. NXF proteins belong to an evolutionarily conserved family of proteins, which are characterized by a leucine-rich-repeat domain (LRR) followed by a region known as the Nuclear Transport Factor 2 (NTF2)-like domain.

Specifications

• Antigen: TAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NXF1
• Gene Alias: Mex 67 homolog; MEX67; Mex67h; modifier of vibrator 1; mRNA export factor TAP; Mvb1; Nuclear RNA export factor 1; nuclear RNA export factor 1 homolog; Nxf1; TAP; tip associated protein; tip associating protein; tip-associated protein; Tip-associating protein; Vdp
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10482, 53319
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 10 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q99JX7, Q9UBU9
• Gene Symbols: NXF1
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human TAP. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG