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Invitrogen™ Tapasin Polyclonal Antibody
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Catalog No. PIPA5102535
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100 μL
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PIPA5102535 100 μL
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Catalog No. PIPA5102535 Supplier Invitrogen™ Supplier No. PA5102535
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TAPBP.

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Tapasin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TAPBP
Gene Accession No. O15533
Gene Alias D17Wsu91e; DADB-159G18.7; NGS17; NGS-17; similar to Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein) (NGS-17); TAP binding protein; TAP binding protein (tapasin); TAPA; tapasin; TAP-associated protein; TAP-binding protein; Tapbp; TPN; TPSN
Gene Symbols TAPBP
Host Species Rabbit
Immunogen A synthesized peptide derived from human TAPBP(Accession O15533), corresponding to amino acid residues P111-V161.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25217, 6892
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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