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Invitrogen™ TAS2R38 Polyclonal Antibody
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Catalog No. PIPA590212
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PIPA590212 100 μL
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Catalog No. PIPA590212 Supplier Invitrogen™ Supplier No. PA590212
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CSCICTVLCV WCFFSRPHFT VTTVLFMNNN TRLNWQIKDL NLFYSFLFCY LWSVPPFLLF LVSSGMLTVS LGRHMRTMKV YTRNSRDPSL EAHIKALKSL V; Positive Samples: rat thymus; Cellular Location: Membrane, Multi-pass membrane protein.

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Variations in TAS2R38 are associated with the ability to taste phenylthiocarbamide (PTC tasting); also called thiourea tasting. The ability to taste the substance PTC and a number of related substances is genetically controlled. Genetic studies have demonstrated complex inheritance for this trait. For some people (and some chimpanzees also), the chemical PTC tastes very bitter. For others, it is tasteless. Actually, substantial variation in taste sensitivity exists in human. Five haplotypes arising from three coding SNPs in the TAS2R38 gene are associated with distinct phenotypes of PTC taste sensitivity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TAS2R38
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.87 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Tas2r138
Gene Accession No. Q4VHE7
Gene Alias mt2r31; PTC; PTC bitter taste receptor; RGD:1560649}; T2R138; T2R26; T2r31; T2r38; T2r38 {ECO:0000312; T2R61; Tas2r138; Tas2r26; TAS2R38; taste 2 receptor member 38; taste receptor type 2 member 26; Taste receptor type 2 member 38; taste receptor type 2 member 61; taste receptor, type 2, member 138; taste receptor, type 2, member 38
Gene Symbols Tas2r138
Host Species Rabbit
Immunogen Synthetic Peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 500091
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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