Invitrogen™ TAS2R4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599931

Catalog No. PIPA599931

Description

Antibody detects endogenous levels of total TAS2R4.

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.

Specifications

• Antigen: TAS2R4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAS2R4
• Gene Alias: bitter taste receptor T2R16; candidate taste receptor T2R4; candidate taste receptor T2R8; MGC163311; mGR08; mt2r8; T2R108; T2R16; T2R20; T2R4; T2R8; Tas2r108; TAS2R4; tas2r4 {ECO:0000250; Tas2r8; taste 2 receptor member 4; taste receptor T2R8; taste receptor type 2 member 20; Taste receptor type 2 member 4; taste receptor type 2 member 8; taste receptor, type 2, member 108; taste receptor, type 2, member 4; UniProtKB:Q9JKT3}
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50832, 554302, 57253
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q67ET0, Q9JKT3, Q9NYW5
• Gene Symbols: Tas2r108, TAS2R4
• Immunogen: A synthesized peptide derived from human TAS2R4(Accession Q9NYW5), corresponding to amino acid residues F49-V99.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG