Invitrogen™ TAUT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553431

Catalog No. PIPA553431

Description

Immunogen sequence: GPFLVRVKYL LTPREPNRWA VEREGATPYN SRTVMNGALV KPTHIIVETM Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.

Taurine is an abundant organic osmolyte that possesses antioxidant and immunomodulatory properties and plays a role in cell volume homeostasis. Taurine is taken up into cells via the taurine transporter (TAUT). TAUT, which is sodium- and chloride-dependent, is a multi-pass membrane protein belonging to the sodium neurotransmitter symporter (SNF) family of proteins. TNF alpha upregulates TAUT expression, while phosphorylation on Serine 322 downregulates it. Overexpression of TAUT protects renal cells from cisplatin-induced nephrotoxicity.

Specifications

• Antigen: TAUT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC6A6
• Gene Alias: AA589629; C80501; MGC10619; MGC131729; OTTHUMP00000208177; OTTHUMP00000208180; SC6A6; Slc6a6; Sodium- and chloride-dependent taurine transporter; Solute carrier 6 ,member 6 (taurine transporter); solute carrier family 6 (neurotransmitter transporter), member 6; solute carrier family 6 (neurotransmitter transporter, taurine), member 6; solute carrier family 6 member 6; solute carrier family 6, member 6; Taurine Transporter; taurine/beta-alanine transporter; TAUT
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6533
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.20 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P31641
• Gene Symbols: SLC6A6
• Immunogen: Recombinant protein corresponding to Human TAUT. Recombinant protein control fragment (Product #RP-91269).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov