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Invitrogen™ TAUT Polyclonal Antibody
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Catalog No. PIPA553431
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100 μL
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PIPA553431 100 μL
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Catalog No. PIPA553431 Supplier Invitrogen™ Supplier No. PA553431
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GPFLVRVKYL LTPREPNRWA VEREGATPYN SRTVMNGALV KPTHIIVETM Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.

Taurine is an abundant organic osmolyte that possesses antioxidant and immunomodulatory properties and plays a role in cell volume homeostasis. Taurine is taken up into cells via the taurine transporter (TAUT). TAUT, which is sodium- and chloride-dependent, is a multi-pass membrane protein belonging to the sodium neurotransmitter symporter (SNF) family of proteins. TNF alpha upregulates TAUT expression, while phosphorylation on Serine 322 downregulates it. Overexpression of TAUT protects renal cells from cisplatin-induced nephrotoxicity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TAUT
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLC6A6
Gene Accession No. P31641
Gene Alias AA589629; C80501; MGC10619; MGC131729; OTTHUMP00000208177; OTTHUMP00000208180; SC6A6; Slc6a6; Sodium- and chloride-dependent taurine transporter; Solute carrier 6 ,member 6 (taurine transporter); solute carrier family 6 (neurotransmitter transporter), member 6; solute carrier family 6 (neurotransmitter transporter, taurine), member 6; solute carrier family 6 member 6; solute carrier family 6, member 6; Taurine Transporter; taurine/beta-alanine transporter; TAUT
Gene Symbols SLC6A6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TAUT. Recombinant protein control fragment (Product #RP-91269).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6533
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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