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Invitrogen™ TBC1D17 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA570937
Description
This target displays homology in the following species: Cow: 93%; Dog: 93%; Goat: 80%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%; Zebrafish: 77%.
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known. [UniProt].
Specifications
TBC1D17 | |
Polyclonal | |
Unconjugated | |
TBC1D17 | |
BC017607; hypothetical protein LOC554092; TBC1 domain family member 17; TBC1 domain family, member 17; TBC1D17; wu:fc56c02; zgc:110443; zgc:110443 protein | |
Rabbit | |
Affinity chromatography | |
RUO | |
233204 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
Q8BYH7 | |
TBC1D17 | |
synthetic peptide directed towards the middle region of mouse TBC1D17. | |
100 μL | |
Primary | |
Mouse | |
Antibody | |
IgG |
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