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Invitrogen™ TBC1D22A Polyclonal Antibody
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Catalog No. PIPA551526
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100 μL
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PIPA551526 100 μL
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Catalog No. PIPA551526 Supplier Invitrogen™ Supplier No. PA551526
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HPASGYVQGI NDLVTPFFVV FICEYIEAEE VDTVDVSGVP AEVLCNIEAD TYWCMSKLLD GIQDNYTFAQ PGIQMKVKML EELVSRIDEQ VHRHLDQHEV RYLQFAFRWM NNLLMREVPL RCTIRLWDTY QSE Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 59%.

TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein that contains one Rab-GAP TBC domain and is thought to function as a GTPase-activating protein for Rab family members. Multiple isoforms of TBC1D22A exist due to alternative splicing events. The gene encoding TBC1D22A maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TBC1D22A
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TBC1D22A
Gene Accession No. Q8WUA7
Gene Alias BC023106; C22orf4; D15Ertd781e; HSC79E021; putative GTPase activator; RGD1306588; TBC1 domain family member 22A; TBC1 domain family, member 22a; TBC1D22A
Gene Symbols TBC1D22A
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TBC1D22A. Recombinant protein control fragment (Product #RP-91366).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25771
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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