Invitrogen™ TBL1X Monoclonal Antibody (4H2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524874

Catalog No. PIMA524874

Description

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.

Specifications

• Antigen: TBL1X
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O60907
• Gene Symbols: Tbl1x
• Immunogen: Purified recombinant human TBL1 protein fragments expressed in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot, Immunocytochemistry
• Clone: 4H2
• Conjugate: Unconjugated
• Gene: Tbl1x
• Gene Alias: 5330429M20; EBI; F-box-like/WD repeat-containing protein TBL1X; RGD1563868; SMAP55; TBL1; Tbl1x; transducin (beta)-like 1 X-linked; transducin (beta)-like 1X-linked; transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked
• Host Species: Mouse
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6907
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid