Invitrogen™ TBL1X Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528644

Catalog No. PIPA528644

Description

Recommended positive controls: HeLaS3. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Chicken (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.

Specifications

• Antigen: TBL1X
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tbl1x
• Gene Alias: 5330429M20; EBI; F-box-like/WD repeat-containing protein TBL1X; RGD1563868; SMAP55; TBL1; Tbl1x; transducin (beta)-like 1 X-linked; transducin (beta)-like 1X-linked; transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6907
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.95 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O60907
• Gene Symbols: Tbl1x
• Immunogen: Synthetic peptide corresponding to a region within amino acids 514 and 577 of Human TBL1X.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG