Invitrogen™ TBL1X/TBL1XR1 Polyclonal Antibody

Catalog No.	Quantity
PIPA131502	50 μg

Catalog No. PIPA131502 Supplier Invitrogen™ Supplier No. PA131502

Description

Goat Polyclonal Antibody

Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX22243-PEP).. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.

Specifications

• Antigen: TBL1X/TBL1XR1
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: TBL1X
• Gene Accession No.: O60907, Q9BZK7
• Gene Alias: 5330429M20; 8030499H02Rik; A630076E03Rik; AW539987; C21; C230089I12Rik; DC42; EBI; F-box-like/WD repeat protein TBL1XR1; F-box-like/WD repeat-containing protein TBL1X; F-box-like/WD repeat-containing protein TBL1XR1; Ira1; MRD41; nuclear receptor co-repressor/HDAC3 complex subunit; nuclear receptor corepressor/HDAC3 complex subunit TBLR1; SMAP55; TBL1; TBL1-related protein 1; Tbl1x; Tbl1xr1; TBLR1; transducin (beta)-like 1 X-linked; transducin (beta)-like 1 X-linked receptor 1; transducin (beta)-like 1X-linked; transducin (beta)-like 1X-linked receptor 1; transducin beta-like 1X-related protein 1; Transducin beta-like protein 1X; transducin-beta-like protein 1, X-linked
• Gene Symbols: TBL1X, Tbl1xr1
• Host Species: Goat
• Immunogen: Peptide with sequence SASDGSVCVLDLRK, from the C Terminus.
• Purification Method: Antigen affinity chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6907, 79718
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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