Invitrogen™ TBL3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560024

Catalog No. PIPA560024

Description

Immunogen sequence: LWKDVTEAEQ AEEQARQEEQ VVRQQELDNL LHEKRYLRAL GLAISLDRPH TVLTVIQAIR RDPEACEKLE ATMLRLRRDQ KEALLRFCVT WNTNSRHCHE AQAVLGVLL Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.

WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.

Specifications

• Antigen: TBL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TBL3
• Gene Alias: 9430070M15Rik; SAZD; Tbl3; transducin (beta)-like 3; transducin beta like 3; transducin beta-like 3; transducin beta-like protein 3; UTP13; WD repeat-containing protein SAZD; WD-repeat protein SAZD
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10607
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q12788
• Gene Symbols: TBL3
• Immunogen: Recombinant protein corresponding to Human TBL3. Recombinant protein control fragment (Product #RP-98792).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG