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TBX1 Mouse anti-Human, Clone: OTI1C2, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF507326

Encompass_Preferred

Catalog No. 50-166-4743


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Specifications

Specifications

TBX1
Monoclonal
Unconjugated
TBX1
CAFS, CATCH22, CTHM, DGCR, DGS, DORV, TBX1C, TGA, VCF, VCFS
Mouse
Affinity Chromatography
RUO
6899
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
OTI1C2
PBS with 8% trehalose and no preservative; pH 7.3
O43435
TBX1
Full length human recombit protein of human TBX1 produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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