Invitrogen™ TBX1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575214

Catalog No. PIPA575214

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: TBX1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TBX1
• Gene Alias: brachyury; CAFS; CATCH22; CTHM; DGCR; DGS; DORV; LOW QUALITY PROTEIN: T-box transcription factor TBX1; T-box 1; T-box 1 transcription factor C; T-box protein 1; T-box transcription factor 1; T-box transcription factor TBX1; T-box transcription factor TBX1; LOW QUALITY PROTEIN: T-box transcription factor TBX1; Tbx1; TBX1C; Testis-specific T-box protein; TGA; VCF; VCFS
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6899
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43435
• Gene Symbols: TBX1
• Immunogen: Synthetic peptide corresponding to amino acids 321-370 of Human TBX1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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