TBX1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-8408	100 μL

Catalog No. 50-198-8408 Supplier Bioss Supplier No. BS8257R

Description

Rabbit Polyclonal Antibody

TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: TBX1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: TBX1
• Gene Accession No.: O43435
• Gene Alias: brachyury; CAFS; CATCH22; CTHM; DGCR; DGS; DORV; T-box 1; T-box 1 transcription factor C; T-box protein 1; T-box transcription factor TBX1; Tbx1; TBX1C; Testis-specific T-box protein; TGA; VCF; VCFS
• Gene Symbols: TBX1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human TBX1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6899
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG