Invitrogen™ TBX5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529845

Catalog No. PIPA529845

Description

Recommended positive controls: HeLa nuclear extract, rat brain. Predicted reactivity: Mouse (100%), Rat (99%), Japanese Medaka (94%), Xenopus laevis (98%), Chicken (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: TBX5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TBX5
• Gene Alias: HOS; T-box 5; T-box protein 5; T-box transcription factor TBX5; TBX5
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 304514, 6910
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.31 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q5I2P1, Q99593
• Gene Symbols: TBX5
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 243 of Human TBX5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG