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Tocris Bioscience™ TC ASK 10
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Catalog No. 482550
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50 mg
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Catalog No. Quantity
48-255-0 50 mg
48-251-0 10 mg
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Catalog No. 48-255-0 Supplier Tocris Bioscience™ Supplier No. 4825/50
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Description

Potent and selective ASK1 inhibitor; orally bioavailable

Potent ASK1 inhibitor (IC50 = 14 nM); displays selectivity for ASK1 over other kinases including ASK2 (IC50 = 0.51 μM), MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf (IC50 values are > 10 μM). Blocks downstream JNK1/p38 phosphorylation in cells. Orally bioavailable.

Chemical Identifiers

CAS 1005775-56-3
Molecular Formula C21H23Cl2N5O

Specifications

Quantity 50 mg
Formula Weight 432.35
Purity >98%
Molecular Weight (g/mol) 432.349
Chemical Name or Material TC ASK 10

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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