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TC ASK 10, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Potent ASK1 inhibitor (IC50 = 14 nM); displays selectivity for ASK1 over other kinases including ASK2 (IC50 = 0.51 μM), MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf (IC50 values are > 10 μM). Blocks downstream JNK1/p38 phosphorylation in cells. Orally bioavailable.
Specifications
Quantity | 50 mg |
Formula Weight | 432.35 |
Percent Purity | >98% |
Chemical Name or Material | TC ASK 10 |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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