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  8. TC-N 1752, Tocris Bioscience™

TC-N 1752, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
1211866-85-1
C25H27F3N6O3
516.525
QLKAFHZJICDACE-UHFFFAOYSA-N
nav1.7 blocker 52, n-2-methyl-3-4-4-4-trifluoromethoxy phenyl methoxy-1-piperidinyl-1,3,5-triazin-2-yl amino phenyl acetamide, n-3-4-4-4-trifluoromethoxy benzyloxy piperidino-1,3,5-triazine-2-ylamino-2-methylphenyl acetamide
53361524
N-[2-methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]piperidin-1-yl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide
CC1=C(C=CC=C1NC(=O)C)NC2=NC=NC(=N2)N3CCC(CC3)OCC4=CC=C(C=C4)OC(F)(F)F
This item is not returnable. View return policy
1211866-85-1
C25H27F3N6O3
516.525
QLKAFHZJICDACE-UHFFFAOYSA-N
nav1.7 blocker 52, n-2-methyl-3-4-4-4-trifluoromethoxy phenyl methoxy-1-piperidinyl-1,3,5-triazin-2-yl amino phenyl acetamide, n-3-4-4-4-trifluoromethoxy benzyloxy piperidino-1,3,5-triazine-2-ylamino-2-methylphenyl acetamide
53361524
N-[2-methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]piperidin-1-yl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide
CC1=C(C=CC=C1NC(=O)C)NC2=NC=NC(=N2)N3CCC(CC3)OCC4=CC=C(C=C4)OC(F)(F)F

Description

NaV channel blocker

Human NaV channel inhibitor (IC50 values are 0.17, 0.3, 0.4, 1.1 and 1.6 μM at hNaV1.7, hNaV1.3, hNaV1.4, hNaV1.5 and hNav1.9 respectively). Also inhibits tetrodotoxin-sensitive sodium channels. Displays analgesic efficacy in the formalin pain model.
Quantity 10mg
Formula Weight 516.52
Percent Purity >99%
Chemical Name or Material TC-N 1752

Safety and Handling

Recommended Storage : Store at +4°C