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Tocris Bioscience™ TC-S 7001 Available on GSA/VA Contract for Federal Government customers only.

Potent and highly selective ROCK inhibitor; orally active

Manufacturer:  Tocris Bioscience™ 4961/1

Catalog No. 49611


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Description

Description

Potent and highly selective ROCK inhibitor (IC50 values are 0.6 and 1.1 nM for ROCK1 and ROCK2, respectively). Exhibits >200-fold selectivity over TRK and FLT3 receptors, and >900-fold selectivity over a panel of other kinases and cardiovascular relevent enzymes and receptors. Reduces blood pressure in normotensive and hypertensive rats. Orally active.

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Specifications

Specifications

6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
867017-68-3
402.79
1mg
>98%
C18H13ClF2N6O
Azaindole-1
Target: Rho-kinase Inhibitors
Safety and Handling

Safety and Handling

Recommended Storage : Store at −20°C

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