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  5. Tocris Bioscience™ TC-S 7009

Tocris Bioscience™ TC-S 7009
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Catalog No. 52435
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Quantity:
5 mg
25 mg
Catalog No. Quantity
52-435 5 mg
52-432-5 25 mg
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Catalog No. 52-435

Supplier: Tocris Bioscience™ 5243/5

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Description

High affinity and selective HIF-2α inhibitor

TC-S 7009 is a high affinity and selective HIF-2α inhibitor (Kd = 81 nM). Binds to the HIF-2α PAS-B domain; disrupts HIF-2α-ARNT heterodimerization. Exhibits >60-fold selectivity for HIF-2α over HIF-1α. Decreases HIF-2α DNA-binding and attenuates expression of HIF-2α target genes in vitro.

Specifications

Chemical Name or Material N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
CAS 1422955-31-4
Assay Percent Range >99%
Quantity 5 mg
Molecular Formula C12H6ClFN4O3
Formula Weight Observed MW: 308.65
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