Tocris Bioscience™ TCB-2

Description

High affinity and potent 5-HT2A agonist

TCB-2 is a high affinity 5-HT2A receptor agonist (Ki values are 0.73 and 0.75 nM for rat and human receptors respectively). Potently stimulates IP3 accumulation in NIH3T3 cells stably expressing rat 5-HT2A receptors (EC50 = 36 nM). Induces head twitches and hypothermia in mice following i.p. administration.

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Specifications

• Chemical Name or Material: (4-Bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine hydrobromide
• CAS: 912342-28-0
• Assay Percent Range: >99%
• Quantity: 50 mg
• Solubility: Soluble to 100mM in DMSO
• Molecular Formula: C₁₁H₁₄BrNO₂.HBr
• Formula Weight: Observed MW: 353.05

For Research Use Only