Invitrogen™ DCAF12 Polyclonal Antibody

Chicken Polyclonal Antibody

Supplier:  Invitrogen™ PA520939

Catalog No. PIPA520939

Description

A suggested positive control is 293 cell lysate. PA5-20939 can be used with blocking peptide PEP-1053.

Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.

Specifications

• Antigen: DCAF12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DCAF12
• Gene Alias: 1500001L20Rik; 5830424K06Rik; AA420338; AI851081; cancer/testis antigen 102; centrosome-related protein TCC52; CT102; Dcaf12; DDB1 and CUL4 associated factor 12; DDB1- and CUL4-associated factor 12; Kiaa1892; LOC682812; similar to WD repeat domain 40A; TCC52; Testis cancer centrosome-related protein; WD repeat domain 40A; WD repeat-containing protein 40A; WDR40A
• Host Species: Chicken
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25853, 682812, 68970
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q5T6F0, Q8BGZ3
• Gene Symbols: DCAF12
• Immunogen: A 15 amino acid peptide near the carboxy terminus of human TCC52.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgY