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Invitrogen™ DCAF12 Polyclonal Antibody
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Catalog No. PIPA520939
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100 μg
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Catalog No. Quantity
PIPA520939 100 μg
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Catalog No. PIPA520939 Supplier Invitrogen™ Supplier No. PA520939
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Description

Chicken Polyclonal Antibody

A suggested positive control is 293 cell lysate. PA5-20939 can be used with blocking peptide PEP-1053.

Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
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Specifications

Antigen DCAF12
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene DCAF12
Gene Accession No. Q5T6F0, Q8BGZ3
Gene Alias 1500001L20Rik; 5830424K06Rik; AA420338; AI851081; cancer/testis antigen 102; centrosome-related protein TCC52; CT102; Dcaf12; DDB1 and CUL4 associated factor 12; DDB1- and CUL4-associated factor 12; Kiaa1892; LOC682812; similar to WD repeat domain 40A; TCC52; Testis cancer centrosome-related protein; WD repeat domain 40A; WD repeat-containing protein 40A; WDR40A
Gene Symbols DCAF12
Host Species Chicken
Immunogen A 15 amino acid peptide near the carboxy terminus of human TCC52.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25853, 682812, 68970
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgY
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