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Invitrogen™ TCCR Polyclonal Antibody
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Catalog No. PIPA519984
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100 μg
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Catalog No. Quantity
PIPA519984 100 μg
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Catalog No. PIPA519984 Supplier Invitrogen™ Supplier No. PA519984
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Description

Rabbit Polyclonal Antibody

In Western blot applications, this antibody detects a band at ~70kDa. A suggested positive control is human spleen tissue lysate. PA5-19984 can be used with blocking peptide PEP-0108.

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells and type 2 (Th2) cells, which are critical for cell-mediated immunity and most antibody responses, respectively. The differentiation of Th1 cells is predominantly under the influence of IL12, while IL4 influences the differentiation of Th2 cells. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but not absent, Th1 or Th2 immune responses. The gene discussed here encodes a protein that is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level and is predicted to be a glycosylated transmembrane protein. Diseases associated with IL27RA include Hyper Ige Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCCR
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Il27ra
Gene Accession No. Q6UWB1
Gene Alias class I cytokine receptor; CRL1; CRL1IL-27R; cytokine receptor family, class 1 (WSXWS), member 1; cytokine receptor WSX-1; Cytokine receptor-like 1; il-27 receptor; IL-27 receptor subunit alpha; IL27R; IL-27R; IL-27R subunit alpha; IL27RA; IL-27RA; IL-27R-alpha; interleukin 27 receptor subunit alpha; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; T cell cytokine receptor; T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; TCCR; T-cell cytokine receptor type 1; Type I T-cell cytokine receptor; UNQ296/PRO336; WSX1; WSX-1; ZcytoR1
Gene Symbols Il27ra
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids near the amino terminus of human TCCR precursor.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9466
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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