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Invitrogen™ TCCR Polyclonal Antibody
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Catalog No. PIPA548004
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100 μg
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PIPA548004 100 μg
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Catalog No. PIPA548004 Supplier Invitrogen™ Supplier No. PA548004
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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 60% cross-reactivity with recombinant human TCCR is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells and type 2 (Th2) cells, which are critical for cell-mediated immunity and most antibody responses, respectively. The differentiation of Th1 cells is predominantly under the influence of IL12, while IL4 influences the differentiation of Th2 cells. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but not absent, Th1 or Th2 immune responses. The gene discussed here encodes a protein that is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level and is predicted to be a glycosylated transmembrane protein. Diseases associated with IL27RA include Hyper Ige Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCCR
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Il27ra
Gene Accession No. O70394
Gene Alias class I cytokine receptor; CRL1; CRL1IL-27R; cytokine receptor family, class 1 (WSXWS), member 1; cytokine receptor WSX-1; Cytokine receptor-like 1; il-27 receptor; IL-27 receptor subunit alpha; IL27R; IL-27R; IL-27R subunit alpha; IL27RA; IL-27RA; IL-27R-alpha; interleukin 27 receptor subunit alpha; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; T cell cytokine receptor; T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; TCCR; T-cell cytokine receptor type 1; Type I T-cell cytokine receptor; UNQ296/PRO336; WSX1; WSX-1; ZcytoR1
Gene Symbols Il27ra
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse IL-27 R alpha/WSX-1/TCCR Gly29-Lys510.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50931
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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