TCEAL1 Mouse anti-Human, Clone: OTI2A1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF807708

Catalog No. 50-166-8431

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TCEAL1 (transcription elongation factor A (SII) protein 3), also known as p21, SIIR or pp21, is a member of the TFS-II family. Transcription elongation factors of the TFS-II family are responsible for releasing RNA polymerase II (Pol II) from transcriptional arrest. DNA arresting sites can result in locked ternary complexes if elongating RNA polymerases are trapped. Transcription elongation factors function to activate the intrinsic RNA cleavage activity of RNA polymerases. This allows the RNA polymerase to cleave the nascent transcript, thereby forming a new 3′-terminus to resume elongation. TCEAL1 is a 157 amino acid nuclear protein that is ubiquitously expressed. TCEAL1 may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA.

Specifications

• Antigen: TCEAL1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TCEAL1
• Gene Alias: SIIR, WEX9, p21, pp21
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9338
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI2A1
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q15170
• Gene Symbols: TCEAL1
• Immunogen: Full length human recombit protein of human TCEAL1 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a