Invitrogen™ TCEAL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536612

Catalog No. PIPA536612

Description

This antibody detects endogenous protein at a molecular weight of 18 kDa. Purity is >95% by SDS-PAGE.

TCEAL1 (transcription elongation factor A (SII) protein 3), also known as p21, SIIR or pp21, is a member of the TFS-II family. Transcription elongation factors of the TFS-II family are responsible for releasing RNA polymerase II (Pol II) from transcriptional arrest. DNA arresting sites can result in locked ternary complexes if elongating RNA polymerases are trapped. Transcription elongation factors function to activate the intrinsic RNA cleavage activity of RNA polymerases. This allows the RNA polymerase to cleave the nascent transcript, thereby forming a new 3'-terminus to resume elongation. TCEAL1 is a 157 amino acid nuclear protein that is ubiquitously expressed. TCEAL1 may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA.

Specifications

• Antigen: TCEAL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TCEAL1
• Gene Alias: 0610011M09Rik; BC011290; Nuclear phosphoprotein p21/SIIR; P21; pp21; SIIR; TCEAL1; TCEA-like protein 1; transcription elongation factor A (SII)-like 1; transcription elongation factor A like 1; transcription elongation factor A protein-like 1; Transcription elongation factor S-II protein-like 1; WEX9
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 237052, 302593, 9338
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15170, Q5PPP3, Q921P9
• Gene Symbols: TCEAL1
• Immunogen: Synthetic peptide corresponding to amino acids 90-143 of human TCEAL1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG