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Invitrogen™ TCEB1 Polyclonal Antibody
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Catalog No. PIPA567489
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PIPA567489 100 μL
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Catalog No. PIPA567489 Supplier Invitrogen™ Supplier No. PA567489
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Rabbit Polyclonal Antibody

Immunogen sequence: ETNEVNFREIP SHVLSKVCMY FTYKVRYTNS STEI Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.

TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCEB1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ELOC
Gene Accession No. Q15369
Gene Alias 2610043E24Rik; 2610301I15Rik; AA407206; AI987979; AW049146; eloC; elongation factor SIII p15 subunit; elongin 15 kDa subunit; elongin C; elongin-C; RNA polymerase II transcription factor SIII subunit C; SIII; SIII p15; Stromal membrane-associated protein SMAP1B homolog; Tceb1; transcription elongation factor B (SIII), polypeptide 1; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); transcription elongation factor B polypeptide 1; transcription elongation factor B polypeptide 1; elongin-C; transcription elongation factor B subunit 1
Gene Symbols ELOC
Host Species Rabbit
Immunogen Recombinant Human TCEB1. Recombinant protein control fragment (Product #RP-108139).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6921
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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