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Invitrogen™ TCEB1 Polyclonal Antibody
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Catalog No. PIPA578189
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100 μL
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PIPA578189 100 μL
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Catalog No. PIPA578189 Supplier Invitrogen™ Supplier No. PA578189
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Description

Rabbit Polyclonal Antibody

Positive Control: Jurkat, Raji, NCI-H929, PC-3 Predicted Reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Cat (100%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCEB1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7
Gene ELOC
Gene Accession No. Q15369
Gene Alias 2610043E24Rik; 2610301I15Rik; AA407206; AI987979; AW049146; eloC; elongation factor SIII p15 subunit; elongin 15 kDa subunit; elongin C; elongin-C; RNA polymerase II transcription factor SIII subunit C; SIII; SIII p15; Stromal membrane-associated protein SMAP1B homolog; Tceb1; transcription elongation factor B (SIII), polypeptide 1; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); transcription elongation factor B polypeptide 1; transcription elongation factor B polypeptide 1; elongin-C; transcription elongation factor B subunit 1
Gene Symbols ELOC
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human TCEB1. The exact sequence is proprietary.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6921
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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