Invitrogen™ TCEB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550802

Catalog No. PA550802

Description

The antibody detects endogenous levels of total TCEB1 protein.

TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

Specifications

• Antigen: TCEB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ELOC
• Gene Alias: 2610043E24Rik; 2610301I15Rik; AA407206; AI987979; AW049146; eloC; elongation factor SIII p15 subunit; elongin 15 kDa subunit; elongin C; elongin-C; RNA polymerase II transcription factor SIII subunit C; SIII; SIII p15; Stromal membrane-associated protein SMAP1B homolog; Tceb1; transcription elongation factor B (SIII), polypeptide 1; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); transcription elongation factor B polypeptide 1; transcription elongation factor B polypeptide 1; elongin-C; transcription elongation factor B subunit 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64525, 67923, 6921
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 2.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P83940, P83941, Q15369
• Gene Symbols: ELOC
• Immunogen: Full length fusion protein of Human TCEB1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG