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TCEB1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550802

Catalog No. PA550802


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Description

Description

The antibody detects endogenous levels of total TCEB1 protein.

TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Specifications

Specifications

TCEB1
Polyclonal
Unconjugated
ELOC
Liquid
ELOC
Full length fusion protein of Human TCEB1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin)
2.2 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q15369, P83940, P83941
SIII, eloC
Rabbit
IgG
100 μL
-20°C
Primary
64525, 67923, 6921
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