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TCF12 Monoclonal Antibody (OTI3C11), TrueMAB™, OriGene
SDP

Catalog No. 501682968
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100 μL
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50-168-2968 100 μL
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Catalog No. 50-168-2968 Supplier OriGene Supplier No. TA809697
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Mouse Monoclonal Antibody

TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.

Specifications

Antigen TCF12
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3C11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TCF12
Gene Accession No. Q99081
Gene Alias CRS3, HEB, HTF4, HsT17266, TCF-12, bHLHb20
Gene Symbols TCF12
Host Species Mouse
Immunogen Full length human recombit protein of human TCF12 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6938
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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