TCF12 Mouse anti-Human, Clone: OTI3C11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF809697

Catalog No. 50-166-9663

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.

Specifications

• Antigen: TCF12
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TCF12
• Gene Alias: CRS3, HEB, HTF4, HsT17266, TCF-12, bHLHb20
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6938
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3C11
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q99081
• Gene Symbols: TCF12
• Immunogen: Full length human recombit protein of human TCF12 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1