TCF12 Mouse anti-Human, Clone: OTI4D6, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-7006	100 μg

Catalog No. 50-166-7006 Supplier OriGene Supplier No. CF804474

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.

Specifications

• Antigen: TCF12
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI4D6
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: TCF12
• Gene Accession No.: Q99081
• Gene Alias: CRS3, HEB, HTF4, HsT17266, TCF-12, bHLHb20
• Gene Symbols: TCF12
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-250 of human TCF12 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6938
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b