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Invitrogen™ TCF12 Polyclonal Antibody
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Catalog No. PIPA566799
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100 μL
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PIPA566799 100 μL
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Catalog No. PIPA566799 Supplier Invitrogen™ Supplier No. PA566799
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FSPPVNSGKTR PTTLGSSQFS GSGIDERGGT TSWGTSGQPS PSYDSSRGFT DSPHYSDHLN DSRLGAHEGL SPTPFMNSNL MGKTSERGSF SLYSRDTGLP GCQSSLLRQD LGLGSPAQLS SSGKPGTAYY SFSATSSRRR P Highest antigen sequence identity to the following orthologs - mouse 96%, rat 96%.

TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCF12
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TCF12
Gene Accession No. Q99081
Gene Alias A130037E08Rik; ALF1; bHLHb20; Class A helix-loop-helix transcription factor ME1; class B basic helix-loop-helix protein 20; CRS3; DNA-binding protein HTF4; E-box-binding protein; HEB; HEBAlt; helix-loop-helix transcription factor 4; HsT17266; HTF4; HTF-4; ME1; Meb; REB; Salivary-specific cAMP response element-binding protein alpha; SCBP alpha; SCBPA; SCBP-alpha; TCF12; TCF-12; Transcription factor 12; transcription factor HTF-4
Gene Symbols TCF12
Host Species Rabbit
Immunogen Recombinant Human TCF12. Recombinant protein control fragment (Product #RP-107458).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6938
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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