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Invitrogen™ TCF12 Polyclonal Antibody
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Catalog No. PIPA578193
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100 μL
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PIPA578193 100 μL
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Catalog No. PIPA578193 Supplier Invitrogen™ Supplier No. PA578193
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Description

Rabbit Polyclonal Antibody

Positive Control: Jurkat, Jurkat nuclear extract Predicted Reactivity: Mouse (89%), Rat (88%), Bovine (97%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCF12
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene TCF12
Gene Accession No. Q99081
Gene Alias A130037E08Rik; ALF1; bHLHb20; Class A helix-loop-helix transcription factor ME1; class B basic helix-loop-helix protein 20; CRS3; DNA-binding protein HTF4; E-box-binding protein; HEB; HEBAlt; helix-loop-helix transcription factor 4; HsT17266; HTF4; HTF-4; ME1; Meb; REB; Salivary-specific cAMP response element-binding protein alpha; SCBP alpha; SCBPA; SCBP-alpha; TCF12; TCF-12; Transcription factor 12; transcription factor HTF-4
Gene Symbols TCF12
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human TCF12. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6938
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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